![]() ![]() In our center, patients with simple obesity often choose SG, while those with diabetes choose either SG or RYGB. Previous research has found that RDW has predictive value in determining the effect of metabolic surgery, but there have been no reports thus far on the predictive effects of MPV on metabolic surgery. A simple and economic indicator that can accurately predict the outcome of surgery in advance may be useful to make the optimum choice of metabolic surgery. Metabolic surgery by Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) has become the most effective treatment for patients with T2DM complicated with obesity. Obesity is an independent risk factor for the development of T2DM. MPV was higher in patients with type 2 diabetes mellitus (T2DM) than in those without T2DM and higher in T2DM patients with microvascular complications (retinopathy or microalbuminuria) than in those without. RDW levels in diabetic patients were significantly higher than in control subjects also, RDW levels in diabetic patients with HbA1c > 7% were significantly higher than in those with HbA1c ≤ 7%. RDW and MPV are also associated with diabetes. In individuals with metabolic syndrome and abdominal obesity, MPV levels were positively correlated with waist circumference and were significantly higher than in those without metabolic syndrome and abdominal obesity. found that RDW was significantly higher in people with a BMI > 35 kg Previous studies have shown a significant correlation between the two indicators and obesity. Cardiovascular risk score and MPV in nonalcoholic fatty liver patients can accurately predict the risk of acute cardiovascular events within 1 year. RDW levels were significantly higher in patients with end point events such as death, heart failure and arrhythmia than in those without end point events. In the last decade, RDW and MPV have both been considered new biomarkers for the prognosis of cardiovascular disease. ![]() Increased MPV is commonly seen in primary thrombocytopenic purpura and myelodysplastic syndrome, while decreased MPV is commonly seen in acute leukemia chemotherapy and aplastic anemia. Mean platelet volume (MPV) is a common indicator of platelet activity in routine blood. ![]() Elevated RDW is commonly seen in iron deficiency anemia, megaloblastic anemia, etc. In previous studies, RDW has been used for the diagnosis and differential diagnosis of erythrocyte disorders, especially anemia, and for the evaluation of nutritional status. It is calculated as the standard deviation (SD) of the distribution of red blood cell volume divided by the mean corpuscular volume (MCV) and then multiplied by 100. Red blood cell distribution width (RDW) is a common indicator in blood routine analysis, which reflects the heterogeneity of red blood cell volume in the circulation. Preoperative baseline RDW and postoperative RDW levels can preliminarily predict the effect of different metabolic surgeries in patients with obesity and DM/IGR. No significant difference in weight index was found in the high and low levels of the MPV before surgery in either group at other follow-up time points. %BW and change in BW and BMI (ΔBW and ΔBMI) at 6 and 12 months after surgery in the high-level RDW (≥ 12.90) before surgery were significantly higher than those in the low level in the RYGB group. In the RYGB group, the RDW level of patients in the high-level percentage weight loss (%BW) (≥ 31.90) at 6 and 12 months after surgery decreased significantly compared to those in the corresponding low level. Twelve months after surgery, the RDW level in the RYGB group was significantly lower than that before surgery. Levels of RDW and MPV in both groups were significantly higher than before 1 month after surgery and then gradually decreased. We retrospectively analyzed the body weight (BW), body mass index (BMI) and blood routine index of 98 patients with obesity and DM/IGR who underwent Roux-en-Y gastric bypass (RYGB) or sleeve gastrectomy (SG). This study aimed to observe the predictive values of RDW and MPV for weight loss after different metabolic surgeries in patients with obesity and abnormal glucose metabolism. Red blood cell distribution width (RDW) and mean platelet volume (MPV) are both new biomarkers for the prognosis of many diseases. ![]()
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